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Moreover, rats exposed to extinction emitted proportionately more ratios that were faster than the previous baseline response rate when compared to haloperidol-treated animals Salamone, Studies of learning indicate that DA systems in general and nucleus accumbens in particular are not only involved in learning related to reinforcement e. The present review will focus upon the effects of drugs and neurochemical manipulations that affect dopamine DA transmission, and how these effects interact with the response requirements, particularly ratio requirements, imposed upon food-reinforced instrumental behavior.
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